Hmm, that's another possibility, you're right—the idea of self-sacrifice in the abstract, or a bit more concretely, of the social rupture that can result from committing to a religion that's different from your family's. It's more commonly discussed in Christianity, I think, in terms of "in the world, but not of it" (John 17:16) and "I come to bring not peace but a sword" (Matthew 10:34). Maybe the Binding of Isaac was the equivalent image for Jews at the time, presented as a question of how much someone is willing to give up, sacrifice, literally murder, etc. for the sake of a god-voice talking to them. But today it seems N/A. It might be understandable as an illustration of "in a bizarre crisis, sometimes people's brains break, and sometimes there are no good options," but the story doesn't generalize to a livable modern religious principle, and it certainly isn't inspirational. That's my perspective as someone who doesn't believe in an anthropomorphic god, anyway.