Another meaning is a physical alteration—by accident, injury, sickness, or age for many men. A different version of that meaning of physical alteration is one that's chosen by many trans/nonbinary people, even though they typically wouldn't use that word because it highlights the loss of masculinity and they'd tend to prefer something like "feminize". Yet another meaning is the stigma that attaches to people who are perceived as falling into one or both of those categories (injured, weak, old, queer, trans, etc.) and that easily attaches to any hypermasculine man who associates with them or who wears a piece of pink clothing. It's not necessarily an actual weakening in body or mind, nor even the perception thereof, but a social judgment of who's in, who's out. If a muscular 33-year-old cis guy is implicitly "emasculated" because he wears pink, what's being implied about disabled people and trans people, for example?